MRPL22 antibody (AA 97-206)

Catalog No. ABIN7268563

This Rabbit Polyclonal antibody specifically detects MRPL22 in WB. It exhibits reactivity toward Human.

Quick Overview for MRPL22 antibody (AA 97-206) (ABIN7268563)

Target: MRPL22 (Mitochondrial Ribosomal Protein L22 (MRPL22))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL22 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRPL22 Antibody

Binding Specificity: AA 97-206

Purpose: MRPL22 Rabbit pAb

Sequence: LAQLEFNDKK GAKIIKEVLL EAQDMAVRDH NVEFRSNLYI AESTSGRGQC LKRIRYHGRG RFGIMEKVYC HYFVKLVEGP PPPPEPPKTA VAHAKEYIQQ LRSRTIVHTL

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 97-206 of human MRPL22 (NP_054899.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MRPL22

Target: MRPL22 (Mitochondrial Ribosomal Protein L22 (MRPL22))

Alternative Name: MRPL22

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene.,MRPL22,HSPC158,L22mt,MRP-L22,MRP-L25,RPML25,Epigenetics & Nuclear Signaling,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial translation,MRPL22

Molecular Weight: 13kDa/14kDa/23kDa

Gene ID: 29093

UniProt: Q9NWU5