NEK4 antibody (AA 1-300)

Catalog No. ABIN7268917

This Rabbit Polyclonal antibody specifically detects NEK4 in WB. It exhibits reactivity toward Human.

Quick Overview for NEK4 antibody (AA 1-300) (ABIN7268917)

Target: NEK4 (NIMA related kinase 4 (NEK4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEK4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NEK4 Antibody

Binding Specificity: AA 1-300

Purpose: NEK4 Rabbit pAb

Sequence: MPLAAYCYLR VVGKGSYGEV TLVKHRRDGK QYVIKKLNLR NASSRERRAA EQEAQLLSQL KHPNIVTYKE SWEGGDGLLY IVMGFCEGGD LYRKLKEQKG QLLPENQVVE WFVQIAMALQ YLHEKHILHR DLKTQNVFLT RTNIIKVGDL GIARVLENHC DMASTLIGTP YYMSPELFSN KPYNYKSDVW ALGCCVYEMA TLKHAFNAKD MNSLVYRIIE GKLPPMPRDY SPELAELIRT MLSKRPEERP SVRSILRQPY IKRQISFFLE ATKIKTSKNN IKNGDSQSKP FATVVSGEAE

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NEK4 (NP_003148.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NEK4

Target: NEK4 (NIMA related kinase 4 (NEK4))

Alternative Name: NEK4

Background: The protein encoded by this gene is a serine/threonine protein kinase required for normal entry into replicative senescence. The encoded protein also is involved in cell cycle arrest in response to double-stranded DNA damage. Finally, this protein plays a role in maintaining cilium integrity, and defects in this gene have been associated with ciliopathies.,NEK4,NRK2,STK2,pp12301,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,NEK4

Molecular Weight: 84kDa/88kDa/94kDa

Gene ID: 6787

UniProt: P51957