NSUN4 antibody (AA 26-290)

Catalog No. ABIN7268944

This Rabbit Polyclonal antibody specifically detects NSUN4 in WB. It exhibits reactivity toward Human.

Quick Overview for NSUN4 antibody (AA 26-290) (ABIN7268944)

Target: NSUN4 (NOL1/NOP2/Sun Domain Family, Member 4 (NSUN4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSUN4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NSUN4 Antibody

Binding Specificity: AA 26-290

Purpose: NSUN4 Rabbit pAb

Sequence: RYKKKWAATE PKFPAVRLAL QNFDMTYSVQ FGDLWPSIRV SLLSEQKYGA LVNNFAAWDH VSAKLEQLSA KDFVNEAISH WELQSEGGQS AAPSPASWAC SPNLRCFTFD RGDISRFPPA RPGSLGVMEY YLMDAASLLP VLALGLQPGD IVLDLCAAPG GKTLALLQTG CCRNLAANDL SPSRIARLQK ILHSYVPEEI RDGNQVRVTS WDGRKWGELE GDTYDRVLVD VPCTTDRHSL HEEENNIFKR SRKKERQILP VLQVQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 26-290 of human NSUN4 (NP_950245.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NSUN4

Target: NSUN4 (NOL1/NOP2/Sun Domain Family, Member 4 (NSUN4))

Alternative Name: NSUN4

Background: Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU maturation by methylation of mitochondrial 12S rRNA, the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU. Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU, the methylation is enhanced by MTERFD/MTERF4.,NSUN4,SHTAP,Epigenetics & Nuclear Signaling,NSUN4

Molecular Weight: 16kDa/21kDa/37kDa/43kDa

Gene ID: 387338

UniProt: Q96CB9