Obscurin antibody

Catalog No. ABIN7269076

This Rabbit Polyclonal antibody specifically detects Obscurin in WB and IF. It exhibits reactivity toward Human.

Quick Overview for Obscurin antibody (ABIN7269076)

Target: Obscurin (OBSCN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Obscurin antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Obscurin Antibody

Purpose: OBSCN Rabbit pAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant protein of human OBSCN.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Obscurin

Target: Obscurin (OBSCN)

Alternative Name: OBSCN

Background: The obscurin gene spans more than 150 kb, contains over 80 exons and encodes a protein of approximately 720 kDa. The encoded protein contains 68 Ig domains, 2 fibronectin domains, 1 calcium/calmodulin-binding domain, 1 RhoGEF domain with an associated PH domain, and 2 serine-threonine kinase domains. This protein belongs to the family of giant sacromeric signaling proteins that includes titin and nebulin, and may have a role in the organization of myofibrils during assembly and may mediate interactions between the sarcoplasmic reticulum and myofibrils. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],ARHGEF30,UNC89,OBSCN,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Motor Proteins,Signal Transduction,OBSCN

Gene ID: 84033

UniProt: Q5VST9

Pathways: Neurotrophin Signaling Pathway