OSTC antibody (C-Term)

Catalog No. ABIN7269094

This Rabbit Polyclonal antibody specifically detects OSTC in WB. It exhibits reactivity toward Human.

Quick Overview for OSTC antibody (C-Term) (ABIN7269094)

Target: OSTC (Oligosaccharyltransferase Complex Subunit (OSTC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OSTC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OSTC Antibody

Binding Specificity: C-Term

Purpose: OSTC Rabbit pAb

Sequence: YDVIVEPPSV GSMTDEHGHQ RPVAFLAYRV NGQYIMEGLA SSFLFTMGGL GFIILDRSNA PNIPKLNRFL LLFIGFVCVL LSFFMARVFM RMKLPGYLMG

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human OSTC (NP_067050.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for OSTC

Target: OSTC (Oligosaccharyltransferase Complex Subunit (OSTC))

Alternative Name: OSTC

Background: Subunit of the oligosaccharyl transferase (OST complex that catalyzes the initial transfer of a defined glycan (Glc(3Man(9GlcNAc(2 in eukaryotes from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER. All subunits are required for a maximal enzyme activity. May be involved in N-glycosylation of APP (amyloid-beta precursor protein. Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1.,OSTC,DC2,Signal Transduction,Endocrine & Metabolism,OSTC

Gene ID: 58505

UniProt: Q9NRP0