PACRG antibody (AA 150-250)

Catalog No. ABIN7269176

The Rabbit Polyclonal anti-PACRG antibody has been validated for WB. It is suitable to detect PACRG in samples from Human.

Quick Overview for PACRG antibody (AA 150-250) (ABIN7269176)

Target: PACRG (PARK2 Co-Regulated (PACRG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PACRG antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PACRG Antibody

Binding Specificity: AA 150-250

Purpose: PACRG Rabbit pAb

Sequence: IIPIKNALNL RNRQVICVTL KVLQHLVVSA EMVGKALVPY YRQILPVLNI FKNMNVNSGD GIDYSQQKRE NIGDLIQETL EAFERYGGEN AFINIKYVVP T

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human PACRG (NP_001073847.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PACRG

Target: PACRG (PARK2 Co-Regulated (PACRG))

Alternative Name: PACRG

Background: This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene.,PACRG,GLUP,HAK005771,PARK2CRG,Cell Biology & Developmental Biology,Ubiquitin,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,PACRG

Molecular Weight: 29kDa/33kDa

Gene ID: 135138

UniProt: Q96M98