PARK7/DJ1 antibody
Quick Overview for PARK7/DJ1 antibody (ABIN7269177)
Target
See all PARK7/DJ1 (PARK7) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- DJ-1/PARK7 Rabbit mAb
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- A synthesized peptide derived from human DJ-1/PARK7
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
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Alternative Name
- PARK7
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Background
- The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008],DJ-1,DJ1,GATD2,HEL-S-67p,PARK7,Cancer,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,G protein signaling,G protein signaling_Small G proteins,Immunology & Inflammation,Neurodegenerative Diseases,Neurodegenerative Diseases Markers,Neurodegenerative Diseases_Dopamine Signaling in Parkinsons Disease,Neuroscience,Signal Transduction,PARK7
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Molecular Weight
- 20kDa
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Gene ID
- 11315
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UniProt
- Q99497
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport
Target
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