PGRMC2 antibody

Catalog No. ABIN7269534

This anti-PGRMC2 antibody is a Rabbit Polyclonal antibody detecting PGRMC2 in WB and IF. Suitable for Human.

Quick Overview for PGRMC2 antibody (ABIN7269534)

Target: PGRMC2 (Progesterone Receptor Membrane Component 2 (PGRMC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGRMC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-PGRMC2 Antibody

Purpose: PGRMC2 Rabbit pAb

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide of human PGRMC2

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PGRMC2

Target: PGRMC2 (Progesterone Receptor Membrane Component 2 (PGRMC2))

Alternative Name: PGRMC2

Background: Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan (By similarity. May serve as a universal non-classical progesterone receptor in the uterus (Probable. Intracellular heme chaperone required for delivery of labile, or signaling heme, to the nucleus (By similarity. Plays a role in adipocyte function and systemic glucose homeostasis. In brown fat, which has a high demand for heme, delivery of labile heme in the nucleus regulates the activity of heme-responsive transcriptional repressors such as NR1D1 and BACH1 (By similarity.,PGRMC2,DG6,PMBP,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,PGRMC2

Molecular Weight: 23kDa/26kDa

Gene ID: 10424

UniProt: O15173

Pathways: Steroid Hormone Mediated Signaling Pathway