PRMT6 antibody

Catalog No. ABIN7269606

This anti-PRMT6 antibody is a Rabbit Monoclonal antibody detecting PRMT6 in WB. Suitable for Human.

Quick Overview for PRMT6 antibody (ABIN7269606)

Target: PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PRMT6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PRMT6 Antibody

Purpose: PRMT6 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human PRMT6

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PRMT6

Target: PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))

Alternative Name: PRMT6

Background: The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011],HRMT1L6,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_Methylation,Epigenetics & Nuclear Signaling,PRMT6

Molecular Weight: 42kDa

Gene ID: 55170

UniProt: Q96LA8