PDIA6 antibody (AA 20-300)

Catalog No. ABIN7269614

The Rabbit Polyclonal anti-PDIA6 antibody has been validated for WB, IHC and IF. It is suitable to detect PDIA6 in samples from Human.

Quick Overview for PDIA6 antibody (AA 20-300) (ABIN7269614)

Target: PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDIA6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Grade: KO Validated

Product Details anti-PDIA6 Antibody

Binding Specificity: AA 20-300

Purpose: [KO Validated] PDIA6 Rabbit pAb

Sequence: LYSSSDDVIE LTPSNFNREV IQSDSLWLVE FYAPWCGHCQ RLTPEWKKAA TALKDVVKVG AVDADKHHSL GGQYGVQGFP TIKIFGSNKN RPEDYQGGRT GEAIVDAALS ALRQLVKDRL GGRSGGYSSG KQGRSDSSSK KDVIELTDDS FDKNVLDSED VWMVEFYAPW CGHCKNLEPE WAAAASEVKE QTKGKVKLAA VDATVNQVLA SRYGIRGFPT IKIFQKGESP VDYDGGRTRS DIVSRALDLF SDNAPPPELL EIINEDIAKR TCEEHQLCVV A

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human PDIA6 (NP_005733.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PDIA6

Target: PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

Alternative Name: PDIA6

Background: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. This protein inhibits the aggregation of misfolded proteins and exhibits both isomerase and chaperone activity. Alternative splicing results in multiple transcript variants encoding different isoforms.,PDIA6,ERP5,P5,TXNDC7,Signal Transduction,PDIA6

Molecular Weight: 47kDa/48kDa/53kDa

Gene ID: 10130

UniProt: Q15084

Pathways: ER-Nucleus Signaling, Cell RedoxHomeostasis