PRTN3 antibody (pArg3)

Catalog No. ABIN7269719

The Rabbit Polyclonal anti-PRTN3 antibody has been validated for WB. It is suitable to detect PRTN3 in samples from Human.

Quick Overview for PRTN3 antibody (pArg3) (ABIN7269719)

Target: PRTN3 (Proteinase 3 (PRTN3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRTN3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PRTN3 Antibody

Binding Specificity: AA 28-170, pArg3

Purpose: Proteinase 3/PR3 Rabbit pAb

Sequence: IVGGHEAQPH SRPYMASLQM RGNPGSHFCG GTLIHPSFVL TAAHCLRDIP QRLVNVVLGA HNVRTQEPTQ QHFSVAQVFL NNYDAENKLN DVLLIQLSSP ANLSASVATV QLPQQDQPVP HGTQCLAMGW GRVGAHDPPA QVL

Cross-Reactivity: Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 28-170 of human Proteinase 3/PR3 (NP_002768.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PRTN3

Target: PRTN3 (Proteinase 3 (PRTN3))

Alternative Name: PRTN3

Background: Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro. By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration. May play a role in neutrophil transendothelial migration, probably when associated with CD177.,ACPA,AGP7,C-ANCA,CANCA,MBN,MBT,NP-4,NP4,P29,PR-3,PR3,PRTN3,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Collagen,PRTN3

Gene ID: 5657

UniProt: P24158