RAB12 antibody (AA 1-70)

Catalog No. ABIN7269796

This Rabbit Polyclonal antibody specifically detects RAB12 in WB. It exhibits reactivity toward Human.

Quick Overview for RAB12 antibody (AA 1-70) (ABIN7269796)

Target: RAB12 (RAB12, Member RAS Oncogene Family (RAB12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAB12 Antibody

Binding Specificity: AA 1-70

Purpose: RAB12 Rabbit pAb

Sequence: MDPGAALQRR AGGGGGLGAG SPALSGGQGR RRKQPPRPAD FKLQVIIIGS RGVGKTSLME RFTDDTFCEA

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human RAB12 (NP_001020471.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RAB12

Target: RAB12 (RAB12, Member RAS Oncogene Family (RAB12))

Alternative Name: RAB12

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy (By similarity.,RAB12,Signal Transduction,G protein signaling,Signal Transduction,RAB12

Molecular Weight: 27kDa

Gene ID: 201475

UniProt: Q6IQ22