Renin antibody

Catalog No. ABIN7269913

This Rabbit Monoclonal antibody specifically detects Renin in WB. It exhibits reactivity toward Human.

Quick Overview for Renin antibody (ABIN7269913)

Target: Renin (REN)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Renin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Renin Antibody

Purpose: Renin Rabbit mAb

Cross-Reactivity: Human

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Renin

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Renin

Target: Renin (REN)

Alternative Name: REN

Background: Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008],HNFJ2,Blood,Blood_Blood Pressure regulation,Cardiovascular,REN

Molecular Weight: 47kDa

Gene ID: 5972

UniProt: P00797

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour