RNF152 antibody (AA 100-200)

Catalog No. ABIN7270063

This Rabbit Polyclonal antibody specifically detects RNF152 in WB. It exhibits reactivity toward Human.

Quick Overview for RNF152 antibody (AA 100-200) (ABIN7270063)

Target: RNF152 (Ring Finger Protein 152 (RNF152))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF152 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RNF152 Antibody

Binding Specificity: AA 100-200

Purpose: RNF152 Rabbit pAb

Sequence: YMLPLPISKE RALLPGDMGC RLLPGSQQKS VTVVTIPAEQ QPLQGGAPQE AVEEEQDRRG VVKSSTWSGV CTVILVACVL VFLLGIVLHN MSCISKRFTV I

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human RNF152 (NP_775828.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RNF152

Target: RNF152 (Ring Finger Protein 152 (RNF152))

Alternative Name: RNF152

Background: E3 ubiquitin-protein ligase mediating 'Lys-63'-linked polyubiquitination of RRAGA in response to amino acid starvation. Thereby, regulates mTORC1 signaling and plays a role in the cellular response to amino acid availability. Also mediates 'Lys-48'-linked polyubiquitination of target proteins and their subsequent targeting to the proteasome for degradation. Induces apoptosis when overexpressed.,RNF152,RNF152

Molecular Weight: 22kDa

Gene ID: 220441

UniProt: Q8N8N0