RNF170 antibody (AA 1-200)

Catalog No. ABIN7270065

Product Details anti-RNF170 Antibody

Target: RNF170 (Ring Finger Protein 170 (RNF170))

Binding Specificity: AA 1-200

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF170 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rnf170 Rabbit pAb

Sequence: MQRYWRFQDN KIQDICFGVL GESWIQRPVM ARYYSEGQSL QQDDSFIEGV SDQVLVAVVV SLALTATLLY ALLRNVQQNI HPENQELVRV LREQFQTEQD VPAPARQQFY TEMYCPICLH QASFPVETNC GHLFCGSCII AYWRYGSWLG AISCPICRQT VTLLLTVFGE DDQSQDVIRL RQDVNDYNRR FSGQPRSIME

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of mouse Rnf170 (NP_084241.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RNF170

Target: RNF170 (Ring Finger Protein 170 (RNF170))

Alternative Name: Rnf170 (RNF170 Products)

Background: This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene.,RNF170,ADSA,SNAX1,Rnf170,Cell Biology & Developmental Biology,Rnf170

Molecular Weight: 16kDa/24kDa/28kDa/33kDa

Gene ID: 77733