RPUSD4 antibody (AA 1-377)

Catalog No. ABIN7270108

This Rabbit Polyclonal antibody specifically detects RPUSD4 in WB. It exhibits reactivity toward Human.

Quick Overview for RPUSD4 antibody (AA 1-377) (ABIN7270108)

Target: RPUSD4 (RNA Pseudouridylate Synthase Domain Containing 4 (RPUSD4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPUSD4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RPUSD4 Antibody

Binding Specificity: AA 1-377

Purpose: RPUSD4 Rabbit pAb

Sequence: MAAPRWSASG PWIRGNGQGC GSLFTLVSKP FCAAAAASTA INAQRLAEKL RAQKREQDTK KEPVSTNAVQ RRVQEIVRFT RQLQRVHPNV LAKALTRGIL HQDKNLVVIN KPYGLPVHGG PGVQLCITDV LPILAKMLHG HKAEPLHLCH RLDKETTGVM VLAWDKDMAH QVQELFRTRQ VVKKYWAITV HVPMPSAGVV DIPIVEKEAQ GQQQHHKMTL SPSYRMDDGK MVKVRRSRNA QVAVTQYQVL SSTLSSALVE LQPITGIKHQ LRVHLSFGLD CPILGDHKYS DWNRLAPQKL SVGTLKKLGL EQSKARYIPL HLHARQLILP ALGSGKEELN LVCKLPRFFV HSLHRLRLEM PNEDQNENNE AKCLGAQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-377 of human RPUSD4 (NP_116184.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RPUSD4

Target: RPUSD4 (RNA Pseudouridylate Synthase Domain Containing 4 (RPUSD4))

Alternative Name: RPUSD4

Background: Catalyzes uridine to pseudouridine isomerization (pseudouridylation of different mitochondrial RNA substrates. Acts on position 1397 in 16S mitochondrial ribosomal RNA (16S mt-rRNA. This modification is required for the assembly of 16S mt-rRNA into a functional mitochondrial ribosome. Acts on position 39 in mitochondrial tRNA(Phe. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA, controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.,RPUSD4,Epigenetics & Nuclear Signaling,RNA Binding,RPUSD4

Molecular Weight: 38kDa/42kDa

Gene ID: 84881

UniProt: Q96CM3