SOSTDC1 antibody (AA 115-206)

Catalog No. ABIN7270163

The Rabbit Polyclonal anti-SOSTDC1 antibody has been validated for WB. It is suitable to detect SOSTDC1 in samples from Human.

Quick Overview for SOSTDC1 antibody (AA 115-206) (ABIN7270163)

Target: SOSTDC1 (Sclerostin Domain Containing 1 (SOSTDC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOSTDC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SOSTDC1 Antibody

Binding Specificity: AA 115-206

Purpose: SOSTDC1 Rabbit pAb

Sequence: GGGYGTKYWS RRSSQEWRCV NDKTRTQRIQ LQCQDGSTRT YKITVVTACK CKRYTRQHNE SSHNFESMSP AKPVQHHRER KRASKSSKHS MS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 115-206 of human SOSTDC1 (NP_056279.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SOSTDC1

Target: SOSTDC1 (Sclerostin Domain Containing 1 (SOSTDC1))

Alternative Name: SOSTDC1

Background: This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death.,SOSTDC1,CDA019,DAND7,ECTODIN,USAG1,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Bone,Growth factor,SOSTDC1

Molecular Weight: 23kDa/26kDa

Gene ID: 25928

UniProt: Q6X4U4