Sialoadhesin/CD169 antibody (AA 50-300)

Catalog No. ABIN7270291

This Rabbit Polyclonal antibody specifically detects Sialoadhesin/CD169 in WB. It exhibits reactivity toward Human.

Quick Overview for Sialoadhesin/CD169 antibody (AA 50-300) (ABIN7270291)

Target: Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sialoadhesin/CD169 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Sialoadhesin/CD169 Antibody

Binding Specificity: AA 50-300

Purpose: SIGLEC1 Rabbit pAb

Sequence: EVPDGITAIW YYDYSGQRQV VSHSADPKLV EARFRGRTEF MGNPEHRVCN LLLKDLQPED SGSYNFRFEI SEVNRWSDVK GTLVTVTEEP RVPTIASPVE LLEGTEVDFN CSTPYVCLQE QVRLQWQGQD PARSVTFNSQ KFEPTGVGHL ETLHMAMSWQ DHGRILRCQL SVANHRAQSE IHLQVKYAPK GVKILLSPSG RNILPGELVT LTCQVNSSYP AVSSIKWLKD GVRLQTKTGV LHLPQAAWSD A

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 50-300 of human SIGLEC1 (NP_075556.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Sialoadhesin/CD169

Target: Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))

Alternative Name: SIGLEC1

Background: This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound, however, the full-length nature of this variant has not been determined.,SN,CD169,SIGLEC-1,SIGLEC1,Immunology & Inflammation,CD markers,SIGLEC1

Molecular Weight: 200kDa

Gene ID: 6614

UniProt: Q9BZZ2