SLIT2 antibody (AA 1330-1529)

Catalog No. ABIN7270336

This Rabbit Polyclonal antibody specifically detects SLIT2 in WB. It exhibits reactivity toward Human.

Quick Overview for SLIT2 antibody (AA 1330-1529) (ABIN7270336)

Target: SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLIT2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SLIT2 Antibody

Binding Specificity: AA 1330-1529

Purpose: Slit2 Rabbit pAb

Sequence: LPGCEPCHKK VCAHGTCQPS SQAGFTCECQ EGWMGPLCDQ RTNDPCLGNK CVHGTCLPIN AFSYSCKCLE GHGGVLCDEE EDLFNPCQAI KCKHGKCRLS GLGQPYCECS SGYTGDSCDR EISCRGERIR DYYQKQQGYA ACQTTKKVSR LECRGGCAGG QCCGPLRSKR RKYSFECTDG SSFVDEVEKV VKCGCTRCVS

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1330-1529 of human Slit2 (NP_004778.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SLIT2

Target: SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))

Alternative Name: SLIT2

Background: This gene encodes a member of the slit family of secreted glycoproteins, which are ligands for the Robo family of immunoglobulin receptors. Slit proteins play highly conserved roles in axon guidance and neuronal migration and may also have functions during other cell migration processes including leukocyte migration. Members of the slit family are characterized by an N-terminal signal peptide, four leucine-rich repeats, nine epidermal growth factor repeats, and a C-terminal cysteine knot. Proteolytic processing of this protein gives rise to an N-terminal fragment that contains the four leucine-rich repeats and five epidermal growth factor repeats and a C-terminal fragment that contains four epidermal growth factor repeats and the cysteine knot. Both full length and cleaved proteins are secreted extracellularly and can function in axon repulsion as well as other specific processes. Alternative splicing results in multiple transcript variants.,SLIT2,SLIL3,Slit-2,Signal Transduction,Neuroscience,SLIT2

Molecular Weight: 168kDa/169kDa

Gene ID: 9353

UniProt: O94813

Pathways: Regulation of Actin Filament Polymerization, Regulation of Cell Size, Smooth Muscle Cell Migration