SLCO1B1 antibody (AA 597-691)

Catalog No. ABIN7270488

This anti-SLCO1B1 antibody is a Rabbit Polyclonal antibody detecting SLCO1B1 in WB. Suitable for Human.

Quick Overview for SLCO1B1 antibody (AA 597-691) (ABIN7270488)

Target: SLCO1B1 (Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLCO1B1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SLCO1B1 Antibody

Binding Specificity: AA 597-691

Purpose: SLCO1B1 Rabbit pAb

Sequence: TTCIKWSTNN CGTRGSCRTY NSTSFSRVYL GLSSMLRVSS LVLYIILIYA MKKKYQEKDI NASENGSVMD EANLESLNKN KHFVPSAGAD SETHC

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 597-691 of human SLCO1B1 (NP_006437.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SLCO1B1

Target: SLCO1B1 (Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1))

Alternative Name: SLCO1B1

Background: This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.,SLCO1B1,HBLRR,LST-1,LST1,OATP-C,OATP1B1,OATP2,OATPC,SLC21A6,Cancer,Endocrine & Metabolism,Lipid Metabolism,SLCO1B1

Molecular Weight: 76kDa

Gene ID: 10599

UniProt: Q9Y6L6