TOPORS antibody

Catalog No. ABIN7270855

This Rabbit Polyclonal antibody specifically detects TOPORS in WB. It exhibits reactivity toward Human.

Quick Overview for TOPORS antibody (ABIN7270855)

Target: TOPORS (Topoisomerase I Binding, arginine/serine-Rich, E3 Ubiquitin Protein Ligase (TOPORS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TOPORS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TOPORS Antibody

Purpose: Topors Rabbit pAb

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant protein of human Topors.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TOPORS

Target: TOPORS (Topoisomerase I Binding, arginine/serine-Rich, E3 Ubiquitin Protein Ligase (TOPORS))

Alternative Name: Topors

Background: Functions as an E3 ubiquitin-protein ligase and as a E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation. May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins. May be involved in DNA-damage-induced cell death through IKBKE sumoylation.,AW105885,LUN,TP53BPL,p53BP3/LUN,Topors,Topors

Gene ID: 106021

UniProt: Q80Z37

Pathways: Maintenance of Protein Location