CG15104 antibody, Dmel\\CG15104 antibody, TOPORS antibody, dTopors antibody, dtopors antibody, fi75f04 antibody, wu:fi75f04 antibody, AW105885 antibody, LUN antibody, TP53BPL antibody, p53BP3/LUN antibody, P53BP3 antibody, RP31 antibody, Topoisomerase I-interacting protein antibody, TOP1 binding arginine/serine rich protein antibody, topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase antibody, topoisomerase I binding, arginine/serine-rich b antibody, topoisomerase I binding, arginine/serine-rich antibody, Topors antibody, TOPORS antibody, topors antibody, toporsb antibody
Background
Functions as an E3 ubiquitin-protein ligase and as a E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation. May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins. May be involved in DNA-damage-induced cell death through IKBKE sumoylation.,AW105885,LUN,TP53BPL,p53BP3/LUN,Topors,Topors