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TMEM100 antibody (C-Term)

This anti-TMEM100 antibody is a Rabbit Polyclonal antibody detecting TMEM100 in WB. Suitable for Human.
Catalog No. ABIN7270950

Quick Overview for TMEM100 antibody (C-Term) (ABIN7270950)

Target

TMEM100 (Transmembrane Protein 100 (TMEM100))

Reactivity

  • 17
  • 1
  • 1
Human

Host

  • 13
  • 4
Rabbit

Clonality

  • 13
  • 4
Polyclonal

Conjugate

  • 9
  • 2
  • 2
  • 2
  • 1
  • 1
This TMEM100 antibody is un-conjugated

Application

  • 13
  • 12
  • 11
  • 9
  • 3
  • 1
  • 1
Western Blotting (WB)
  • Binding Specificity

    • 8
    • 4
    • 2
    • 1
    C-Term

    Purpose

    TMEM100 Rabbit pAb

    Sequence

    ELSCYRCIIP FAVVVFIAGI VVTAVAYSFN SHGSIISIFG LVVLSSGLFL LASSALCWKV RQRSKKAKRR ESQTALVANQ RSLFA

    Cross-Reactivity

    Human, Mouse

    Characteristics

    Polyclonal Antibodies

    Purification

    Affinity purification

    Immunogen

    A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human TMEM100 (NP_001093110.1).

    Isotype

    IgG
  • Application Notes

    WB,1:500 - 1:2000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    TMEM100 (Transmembrane Protein 100 (TMEM100))

    Alternative Name

    TMEM100

    Background

    Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Involved in the regulation of nociception, acting as a modulator of the interaction between TRPA1 and TRPV1, two molecular sensors and mediators of pain signals in dorsal root ganglia (DRG neurons. Mechanistically, it weakens their interaction, thereby releasing the inhibition of TRPA1 by TRPV1 and increasing the single-channel open probability of the TRPA1-TRPV1 complex.,TMEM100,TMEM100

    Molecular Weight

    14kDa

    Gene ID

    55273

    UniProt

    Q9NV29
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