TMEM2 antibody

Catalog No. ABIN7270962

This anti-TMEM2 antibody is a Rabbit Polyclonal antibody detecting TMEM2 in WB. Suitable for Human.

Quick Overview for TMEM2 antibody (ABIN7270962)

Target: TMEM2 (Transmembrane Protein 2 (TMEM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TMEM2 Antibody

Purpose: TMEM2 Rabbit pAb

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant protein of human TMEM2.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TMEM2

Target: TMEM2 (Transmembrane Protein 2 (TMEM2))

Alternative Name: TMEM2

Background: This gene encodes a type II transmembrane protein that belongs to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation of the JAK STAT signaling pathway. The activation of this gene by transcription factor SOX4 in breast cancer cells has been shown to mediate the pathological effects of SOX4 on cancer progression. Naturally occurring mutations in this gene are associated with autosomal recessive non-syndromic hearing loss. [provided by RefSeq, Mar 2017],TMEM2,Cell Biology & Developmental Biology,TMEM2

Gene ID: 23670

UniProt: Q9UHN6