TMEM59
Reactivity: Mouse
WB, IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 488
Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
TMEM59
(Transmembrane Protein 59 (TMEM59))
Alternative Name
TMEM59
Background
This gene encodes a protein shown to regulate autophagy in response to bacterial infection. This protein may also regulate the retention of amyloid precursor protein (APP) in the Golgi apparatus through its control of APP glycosylation. Overexpression of this protein has been found to promote apoptosis in a glioma cell line. Alternative splicing results in multiple transcript variants.,TMEM59,C1orf8,DCF1,HSPC001,PRO195,UNQ169,Signal Transduction,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,TMEM59