TRIM2 antibody (AA 100-300)

Catalog No. ABIN7270979

The Rabbit Polyclonal anti-TRIM2 antibody has been validated for WB and IHC. It is suitable to detect TRIM2 in samples from Human.

Quick Overview for TRIM2 antibody (AA 100-300) (ABIN7270979)

Target: TRIM2 (Tripartite Motif Containing 2 (TRIM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TRIM2 Antibody

Binding Specificity: AA 100-300

Purpose: TRIM2 Rabbit pAb

Sequence: GVAALQNNFF ITNLMDVLQR TPGSNAEESS ILETVTAVAA GKPLSCPNHD GNVMEFYCQS CETAMCRECT EGEHAEHPTV PLKDVVEQHK ASLQVQLDAV NKRLPEIDSA LQFISEIIHQ LTNQKASIVD DIHSTFDELQ KTLNVRKSVL LMELEVNYGL KHKVLQSQLD TLLQGQESIK SCSNFTAQAL NHGTETEVLL V

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-300 of human TRIM2 (NP_056086.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TRIM2

Target: TRIM2 (Tripartite Motif Containing 2 (TRIM2))

Alternative Name: TRIM2

Background: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants.,TRIM2,CMT2R,RNF86,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,TRIM2

Molecular Weight: 81kDa/84kDa

Gene ID: 23321

UniProt: Q9C040