Ubiquilin 1 antibody (AA 480-540)

Catalog No. ABIN7271122

This Rabbit Polyclonal antibody specifically detects Ubiquilin 1 in WB. It exhibits reactivity toward Human.

Quick Overview for Ubiquilin 1 antibody (AA 480-540) (ABIN7271122)

Target: Ubiquilin 1 (UBQLN1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ubiquilin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Ubiquilin 1 Antibody

Binding Specificity: AA 480-540

Purpose: UBQLN1 Rabbit pAb

Sequence: LIPGFTPGLG ALGSTGGSSG TNGSNATPSE NTSPTAGTTE PGHQQFIQQM LQALAGVNPQ L

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 480-540 of human UBQLN1 (NP_038466.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Ubiquilin 1

Target: Ubiquilin 1 (UBQLN1)

Alternative Name: UBQLN1

Background: This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.,UBQLN1,DA41,DSK2,PLIC-1,UBQN,XDRP1,Cell Biology & Developmental Biology,Ubiquitin,UBQLN1

Molecular Weight: 18kDa/43kDa/59kDa/62kDa

Gene ID: 29979

UniProt: Q9UMX0