UBE4B antibody (AA 130-250)

Catalog No. ABIN7271133

This anti-UBE4B antibody is a Rabbit Polyclonal antibody detecting UBE4B in WB. Suitable for Human.

Quick Overview for UBE4B antibody (AA 130-250) (ABIN7271133)

Target: UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE4B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UBE4B Antibody

Binding Specificity: AA 130-250

Purpose: UBE4B Rabbit pAb

Sequence: EVDENDRREK RSLSDKEPSS GPEVSEEQAL QLVCKIFRVS WKDRDRDVIF LSSLSAQFKQ NPKEVFSDFK DLIGQILMEV LMMSTQTRDE NPFASLTATS QPIAAAARSP DRNLLLNTGS N

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 130-250 of human UBE4B (NP_006039.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UBE4B

Target: UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))

Alternative Name: UBE4B

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],E4,HDNB1,UBOX3,UFD2,UFD2A,UBE4B,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,UBE4B

Molecular Weight: 121kDa/133kDa/146kDa/151kDa

Gene ID: 10277

UniProt: O95155