UGT1A10 antibody (AA 50-150)

Catalog No. ABIN7271191

This Rabbit Polyclonal antibody specifically detects UGT1A10 in WB. It exhibits reactivity toward Human.

Quick Overview for UGT1A10 antibody (AA 50-150) (ABIN7271191)

Target: UGT1A10 (UDP Glucuronosyltransferase 1 Family, Polypeptide A10 (UGT1A10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UGT1A10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UGT1A10 Antibody

Binding Specificity: AA 50-150

Purpose: UGT1A10 Rabbit pAb

Sequence: LRGHEVVVVM PEVSWQLERS LNCTVKTYST SYTLEDQNRE FMVFAHAQWK AQAQSIFSLL MSSSSGFLDL FFSHCRSLFN DRKLVEYLKE SSFDAVFLDP F

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human UGT1A10 (NP_061948.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UGT1A10

Target: UGT1A10 (UDP Glucuronosyltransferase 1 Family, Polypeptide A10 (UGT1A10))

Alternative Name: UGT1A10

Background: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and quinolines.,UGT1A10;UDPGT;UGT-1J;UGT1-10;UGT1.10;UGT1J,Signal Transduction,Endocrine & Metabolism,Drug metabolism,UGT1A10

Molecular Weight: 49kDa/59kDa

Gene ID: 54575

UniProt: Q9HAW8

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha