WNT10A antibody (AA 158-417)

Catalog No. ABIN7271374

This Rabbit Polyclonal antibody specifically detects WNT10A in WB. It exhibits reactivity toward Human.

Quick Overview for WNT10A antibody (AA 158-417) (ABIN7271374)

Target: WNT10A (Wingless-Type MMTV Integration Site Family, Member 10A (WNT10A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNT10A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-WNT10A Antibody

Binding Specificity: AA 158-417

Purpose: WNT10A Rabbit pAb

Sequence: GCDASRRGDE EAFRRKLHRL QLDALQRGKG LSHGVPEHPA LPTASPGLQD SWEWGGCSPD MGFGERFSKD FLDSREPHRD IHARMRLHNN RVGRQAVMEN MRRKCKCHGT SGSCQLKTCW QVTPEFRTVG ALLRSRFHRA TLIRPHNRNG GQLEPGPAGA PSPAPGAPGP RRRASPADLV YFEKSPDFCE REPRLDSAGT VGRLCNKSSA GSDGCGSMCC GRGHNILRQT RSERCHCRFH WCCFVVCEEC RITEWVSVCK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 158-417 of human WNT10A (NP_079492.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for WNT10A

Target: WNT10A (Wingless-Type MMTV Integration Site Family, Member 10A (WNT10A))

Alternative Name: WNT10A

Background: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region.,WNT10A,OODD,SSPS,STHAG4,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Tumor suppressors,Signal Transduction,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Stem Cells,WNT10A

Molecular Weight: 46kDa

Gene ID: 80326

UniProt: Q9GZT5

Pathways: WNT Signaling