Recombinant SARS-CoV-2 Spike antibody (RBD)

Catalog No. ABIN7271721

This anti-SARS-CoV-2 Spike antibody is a Mouse Chimeric antibody detecting SARS-CoV-2 Spike in ELISA, SR, ISt and in vitro. Suitable for SARS Coronavirus-2 (SARS-CoV-2).

Quick Overview for Recombinant SARS-CoV-2 Spike antibody (RBD) (ABIN7271721)

Target: SARS-CoV-2 Spike

Antibody Type: Recombinant Antibody

Reactivity: SARS Coronavirus-2 (SARS-CoV-2)

Host: Mouse

Clonality: Chimeric

Conjugate: This SARS-CoV-2 Spike antibody is un-conjugated

Application: ELISA, Spike and Recovery (SR), Immunostaining (ISt), In vitro Assay (in vitro)

Grade: MALS verified

Clone: AM130

Product Details anti-SARS-CoV-2 Spike Antibody

Binding Specificity: RBD

Purpose: Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AM130) (Trehalose free) (MALS verified)

Specificity: This product can recognize SARS-CoV-2 and SARS-CoV Spike protein RBD domain. No cross-reactivity is detected with Spike protein RBD domain of other coronaviruses, including MERS-CoV, HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1.

Characteristics: Recombinant Antibodies produced in HEK293. Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AM130) is a chimeric monoclonal antibody combining the constant domains of the human IgG1 molecule with mouse variable regions. The variable region was obtained from a mouse immunized with purified recombinant SARS-CoV-2 Spike S1 Protein.

Immunogen: Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AM130) (ABIN7271721 and ABIN7273310) is a chimeric monoclonal antibody combining the constant domains of the human IgG1 molecule with mouse variable regions. The variable region was obtained from a mouse immunized with purified recombinant SARS-CoV-2 Spike S1 Protein.

Isotype: IgG1

Application Details

Application Notes: This antibody is developed for detecting the SARS-CoV-2 Spike Protein in cell supernatant or SARS-CoV-2 virus in vitro by sandwich ELISA assay.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -80 °C

Storage Comment: -70°C

Target Details for SARS-CoV-2 Spike

Target: SARS-CoV-2 Spike

Background: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.