Recombinant SARS-CoV-2 Spike antibody (RBD)

Catalog No. ABIN7271730

This anti-SARS-CoV-2 Spike antibody is a Mouse Monoclonal antibody detecting SARS-CoV-2 Spike in Neut. Suitable for SARS Coronavirus-2 (SARS-CoV-2).

Quick Overview for Recombinant SARS-CoV-2 Spike antibody (RBD) (ABIN7271730)

Target: SARS-CoV-2 Spike

Antibody Type: Recombinant Antibody

Reactivity: SARS Coronavirus-2 (SARS-CoV-2)

Host: Mouse

Clonality: Monoclonal

Conjugate: This SARS-CoV-2 Spike antibody is un-conjugated

Application: Neutralization (Neut)

Clone: AM122

Product Details anti-SARS-CoV-2 Spike Antibody

Binding Specificity: RBD

Purpose: Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Mouse IgG1 (AM122)

Specificity: This product is a specific antibody against SARS-CoV-2 Spike protein RBD domain. Cross-reactivity with Spike protein RBD domain of other coronaviruses, including SARS-CoV, MERS-CoV, HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1 has not been tested.

Characteristics: Recombinant Antibodies produced in HEK293. Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Mouse IgG1 (AM122), originally from mouse immunized with recombinant SARS-CoV-2 Spike RBD protein, is recombinantly expressed from HEK293 cells.

Immunogen: Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Mouse IgG1 (AM122) (ABIN7271730 and ABIN7273319), originally from mouse immunized with recombinant SARS-CoV-2 Spike RBD protein, is recombinantly expressed from HEK293 cells.

Isotype: IgG1

Application Details

Restrictions: For Research Use only

Handling

Format: Powder

Storage: -20 °C

Storage Comment: -20°C

Target Details for SARS-CoV-2 Spike

Target: SARS-CoV-2 Spike

Background: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.