Recombinant SARS-CoV-2 Spike antibody (RBD)

Catalog No. ABIN7271733

This anti-SARS-CoV-2 Spike antibody is a Human Chimeric antibody detecting SARS-CoV-2 Spike in . Suitable for SARS Coronavirus-2 (SARS-CoV-2) and SARS CoV-2 Delta.

Quick Overview for Recombinant SARS-CoV-2 Spike antibody (RBD) (ABIN7271733)

Target: SARS-CoV-2 Spike

Antibody Type: Recombinant Antibody

Reactivity: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Delta

Host: Human

Clonality: Chimeric

Conjugate: This SARS-CoV-2 Spike antibody is un-conjugated

Application: Please inquire

Clone: AM110

Product Details anti-SARS-CoV-2 Spike Antibody

Binding Specificity: RBD

Purpose: Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AM110) (Delta Specific)

Specificity: This product is a specific antibody against SARS-CoV-2 Spike protein RBD domain. Cross-reactivity with Spike protein RBD domain of other coronaviruses, including SARS-CoV, MERS-CoV, HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1, has not been tested.

Characteristics: Recombinant Antibodies produced in HEK293. Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (Delta Specific) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike RBD protein. The antibody is specific against the Delta (B.1.617.2/AY.4) variant of SARS-CoV-2, and has no binding with the spike RBD of the wild type virus and the Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), Omicron (B.1.1.529/BA.1) variant.

Immunogen: Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (Delta Specific) is a chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike RBD protein. The antibody is specific against the Delta (B.1.617.2/AY.4) variant of SARS-CoV-2, and has no binding with the spike RBD of the wild type virus and the Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), Omicron (B.1.1.529/BA.1) variant.

Isotype: IgG1

Application Details

Restrictions: For Research Use only

Handling

Format: Powder

Storage: -20 °C

Storage Comment: -20°C

Target Details for SARS-CoV-2 Spike

Target: SARS-CoV-2 Spike

Background: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.