Recombinant SARS-CoV-2 Spike antibody (RBD)

Catalog No. ABIN7271752

This Human Monoclonal antibody specifically detects SARS-CoV-2 Spike in Neut. It exhibits reactivity toward SARS Coronavirus-2 (SARS-CoV-2).

Quick Overview for Recombinant SARS-CoV-2 Spike antibody (RBD) (ABIN7271752)

Target: SARS-CoV-2 Spike

Antibody Type: Recombinant Antibody

Reactivity: SARS Coronavirus-2 (SARS-CoV-2)

Host: Human

Clonality: Monoclonal

Conjugate: This SARS-CoV-2 Spike antibody is un-conjugated

Application: Neutralization (Neut)

Grade: MALS verified

Clone: AM359b

Product Details anti-SARS-CoV-2 Spike Antibody

Binding Specificity: RBD

Purpose: Anti-SARS-CoV-2 Spike RBD Broadly Neutralizing Antibody, Human IgG1 (AM359b) (MALS verified)

Specificity: This product is a specific antibody specifically reacts with This product is a specific antibody against SARS-CoV-2 Spike protein RBD domain. Cross-reactivity with Spike protein RBD domain of other coronaviruses, including SARS-CoV, MERS-CoV, HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1 has not been tested.

Characteristics: Recombinant Antibodies produced in HEK293. Anti-SARS-CoV-2 Spike RBD Broadly Neutralizing Antibody, Human IgG1 is isolated from a Spike RBD infected Human and is recombinantly produced from human 293 cells (HEK293)

Immunogen: The antibody is isolated from the serum of COVID-19 vaccine recipient and is recombinantly produced from human 293 cells (HEK293). This antibody can broadly neutralize SARS-CoV-2 Variants of Concerns (VOCs) including Alpha, Beta, Gamma, Delta and Omicron.

Isotype: IgG1

Application Details

Restrictions: For Research Use only

Handling

Format: Powder

Storage: -20 °C

Storage Comment: -20°C

Target Details for SARS-CoV-2 Spike

Target: SARS-CoV-2 Spike

Background: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.