GCET2 antibody (AA 31-130)

Catalog No. ABIN717731

The Rabbit Polyclonal anti-GCET2 antibody has been validated for ELISA, WB, IF (cc), IF (p), IHC (fro) and IHC (p). It is suitable to detect GCET2 in samples from Mouse.

Quick Overview for GCET2 antibody (AA 31-130) (ABIN717731)

Target: GCET2 (Germinal Center Expressed Transcript 2 (GCET2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCET2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GCET2 Antibody

Binding Specificity: AA 31-130

Cross-Reactivity: Mouse

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GCET2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GCET2

Target: GCET2 (Germinal Center Expressed Transcript 2 (GCET2))

Alternative Name: Gcet2

Background:

Synonyms: HGAL, GCAT2, GCET2, Germinal center-associated signaling and motility protein, Germinal center B-cell-expressed transcript 2 protein, Germinal center-associated lymphoma protein, GCSAM, GAL

Background: Involved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6. Serves as a positive regulator of the RhoA signaling pathway. Enhancement of RhoA activation results in inhibition of lymphocyte and lymphoma cell motility by activation of its downstream effector ROCK. Is a regulator of B-cell receptor signaling, that acts through SYK kinase activation.

Gene ID: 257144

UniProt: Q8N6F7