MERS-CoV Nucleocapsid antibody

Catalog No. ABIN7383849

The Rabbit Polyclonal anti-MERS-CoV Nucleocapsid antibody has been validated for WB. It is suitable to detect MERS-CoV Nucleocapsid in samples from Middle East Respiratory Syndrome Coronavirus (MERS-CoV).

Quick Overview for MERS-CoV Nucleocapsid antibody (ABIN7383849)

Target: MERS-CoV Nucleocapsid (MERS-CoV N) (MERS-Coronavirus Nucleocapsid Protein (MERS-CoV N))

Reactivity: Middle East Respiratory Syndrome Coronavirus (MERS-CoV)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MERS-CoV Nucleocapsid antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MERS-CoV Nucleocapsid Antibody

Specificity: Anti-MERS-CoV Nucleocapsid Protein Polyclonal Antibody

Purification: Antigen Affinity

Immunogen: A synthetic peptide corresponding to the center region of MERS-CoV (NCoV / Novel coronavirus) Nucleocapsid Protein (NP protein)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 0.2 μm filtered solution in PBS

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MERS-CoV Nucleocapsid

Target: MERS-CoV Nucleocapsid (MERS-CoV N) (MERS-Coronavirus Nucleocapsid Protein (MERS-CoV N))

Alternative Name: MERS-CoV Nucleocapsid Protein

Background: Coronavirus NP,coronavirus Nucleocapsid,coronavirus Nucleoprotein,cov np,ncov NP,novel coronavirus Nucleoprotein,NP,Nucleocapsid,Nucleoprotein,Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.