NAT10 antibody
Quick Overview for NAT10 antibody (ABIN7384312)
Target
See all NAT10 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purification
- Affinity Purified
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Isotype
- IgG
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Application Notes
- WB 1:500-1:1000 IF 1:100-1:200
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Restrictions
- For Research Use only
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Concentration
- 300 μg/mL
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Buffer
- 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- NAT10 (N-Acetyltransferase 10 (GCN5-Related) (NAT10))
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Alternative Name
- NAT10
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Background
- ALP,DKFZp434C116,FLJ10774,FLJ12179,FLJ23850,hALP,KIAA1709,N acetyltransferase 10,N acetyltransferase 10 GCN5 related,N acetyltransferase like,N acetyltransferase like protein,N-acetyltransferase 10,NAT10,NAT10,NET43,NAT-10 (N-acetyltransferase 10) is a nuclear protein that belongs to the UPF0202 family. It has a single N-acetyltransferase domain that likely functions as a histone acetyltransferase. NAT10 functions primarily to regulate the activity of telomerase. It is upregulated in response to DNA damage and is likely to take part in genotoxic resistance and DNA repair. NAT-10 has a high binding potential for the promoter region of TERT which stimulates the production of telomerase. These varieties of function imply that human telomerase complexes have multiple functions rather than specific duties.
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Molecular Weight
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Observed_MW: 116kDa
Calculated_MW: 116kDa
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Gene ID
- 55226
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UniProt
- Q9H0A0
Target
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