FKBP4 antibody

Catalog No. ABIN7384354

This anti-FKBP4 antibody is a Rabbit Monoclonal antibody detecting FKBP4 in WB and IF. Suitable for Human, Mouse, Rat and Hamster.

Quick Overview for FKBP4 antibody (ABIN7384354)

Target: FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

Reactivity: Human, Mouse, Rat, Hamster

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FKBP4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: R03-4A3

Product Details anti-FKBP4 Antibody

Purification: Affinity Purified

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000 IF 1:20-1:50

Restrictions: For Research Use only

Handling

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FKBP4

Target: FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

Alternative Name: FKBP52

Background: 51 kDa FK506-binding protein,52 kDa FK506 binding protein,52 kDa FK506-binding protein,52 kDa FKBP,59 kDa immunophilin,FK506 binding protein 4,FK506-binding protein 4,FKBP 4,FKBP 52,FKBP 59,FKBP-4,FKBP-52,FKBP4,FKBP4,FKBP51,FKBP52 protein,FKBP59,HBI,Hsp 56,HSP binding immunophilin,HSP-binding immunophilin,Hsp56,Immunophilin FKBP52,N-terminally processed,p52,p59,p59 protein,Peptidyl prolyl cis trans isomerase,Peptidyl-prolyl cis-trans isomerase FKBP4,Peptidylprolyl cis trans isomerase,PPIase,PPIase FKBP4,Rotamase,T cell FK506 binding protein 59kD,FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family that comprises intracellular protein effectors of immunosuppressive drugs,and it is known as a steroid receptor-associated protein. As a novel regulator of microtubule dynamics,FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. FKBP52 is highly expressed in CNS regions susceptible to Alzheimer's,and plays a role in modulating toxicity of Abeta peptides. The protein can associate with the Tau function,and may help to decipher and modulate the events involved in Tau-induced neurodegeneration. In addition,FKBP52 is likely to play a role in growth and development of the male genitalia.

Molecular Weight:

Observed_MW: 52kDa

Calculated_MW: 52kDa

Gene ID: 2288

UniProt: Q02790

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway