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Recombinant IL5 (Mepolizumab Biosimilar) antibody

This Mammalian Cells Monoclonal antibody specifically detects IL5 (Mepolizumab Biosimilar) in ELISA. It exhibits reactivity toward Human.
Catalog No. ABIN7487818
$336.06
Plus shipping costs $50.00
Shipping to: United States
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Quick Overview for Recombinant IL5 (Mepolizumab Biosimilar) antibody (ABIN7487818)

Target

IL5 (Mepolizumab Biosimilar)

Antibody Type

Recombinant Antibody

Reactivity

Human

Host

  • 2
  • 1
Mammalian Cells

Clonality

  • 2
  • 1
Monoclonal

Conjugate

  • 3
This IL5 (Mepolizumab Biosimilar) antibody is un-conjugated

Application

  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA

Grade

Research Grade
  • Expression System

    Mammalian cells

    Purpose

    Mepolizumab Biosimilar - Anti-IL5 mAb

    Characteristics

    Antibody Type: IgG1-kappa

    Purification

    Recombinant antibody expressed in mammalien cells and purified.

    Isotype

    IgG1 kappa
  • Restrictions

    For Research Use only
  • Buffer

    PBS pH 7.5

    Storage

    -80 °C

    Storage Comment

    store at -80°C
  • Target

    IL5 (Mepolizumab Biosimilar)

    Target Type

    Biosimilar

    Background

    SB-240563
    Mepolizumab is a fully humanized recombinant IgG1 kappa monoclonal antibody directed against IL-5 produced in Chinese hamster ovary cells. (EGPA) and eosinophilia syndrome (HES). The pathogenesis of eosinophils is complex, but IL-5 is considered a key eosinophilic factor, involved in the differentiation, recruitment, activation and prolonged survival of eosinophils in peripheral tissues. Activated eosinophils further stimulate the inflammatory response, and also induce tissue damage and promote fibrosis, all of which contribute to the multifactorial symptoms of eosinophilic disease. Mepolizumab is used to treat severe asthma.

    CAS-No

    196078-29-2
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