Cullin 3 antibody (AA 650-700)

Catalog No. ABIN7448504

The Rabbit Polyclonal anti-Cullin 3 antibody has been validated for IHC. It is suitable to detect Cullin 3 in samples from Human.

Quick Overview for Cullin 3 antibody (AA 650-700) (ABIN7448504)

Target: Cullin 3 (CUL3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cullin 3 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Cullin 3 Antibody

Binding Specificity: AA 650-700

Purpose: Rabbit anti-Cul3 IHC Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,Zebrafish,X. laevis,X. tropicalis,Chicken,Turkey,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,Duckbill platypus,White-tufted-ear marmoset,West Indian ocean coelacanth,Tasmanian devil,Nile tilapia,Japanese pufferfish,Thirteen-lined ground squirrel,Little brown bat,Green anole,Small-eared galago,Chinese hamster,Naked mole rat,Gray short-tailed opossum,Medaka fish,Spotted green pufferfish,African elephant,Zebra finch,Three-spined stickleback,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogen: Between AA 650 and 700

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Cullin 3

Target: Cullin 3 (CUL3)

Alternative Name: Cul3

Background: Background: Cul3 is a member of the cullin group of proteins and functions as a scaffold to bring together ubiquitin E3 ligases, E2 conjugating enzyme, and substrate proteins to mediate the ubiquitination of substrate proteins. Cul3 and its associated ubiquitin ligase activity are essential for mitotic division and required for correct alignment of chromosomes and the completion of cytokinesis. Aurora B is a substrate of Cul3-based E3 ubiquitin ligase activity.

Gene ID: 8452

NCBI Accession: NP_003581

UniProt: Q13618

Pathways: M Phase