INPPL1 antibody (AA 100-150)

Catalog No. ABIN7448605

This Rabbit Polyclonal antibody specifically detects INPPL1 in IHC. It exhibits reactivity toward Human.

Quick Overview for INPPL1 antibody (AA 100-150) (ABIN7448605)

Target: INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INPPL1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-INPPL1 Antibody

Binding Specificity: AA 100-150

Purpose: Rabbit anti-INPPL1/SHIP2 IHC Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,Rabbit,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Chinese hamster,Naked mole rat,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogen: Between AA 100 and 150

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for INPPL1

Target: INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))

Alternative Name: INPPL1/SHIP2

Background: Background: INPPL1 (Inositol Polyphosphate Phosphatase-Like Protein 1) is a phosphatidylinositol phosphatase that negatively regulates phosphoinositide 3-kinase (PI3K) pathways related to numerous cell activities. INPPL1 plays a role in PI3K-dependent insulin, macrophage colony-stimulating factor, and EGF signaling. INPPL1 is also involved in actin cytoskeletal remodeling, actin dynamics, and neuritogenesis. INPPL1 interacts with SHC1 (src-homology domain) to mediate EGFR signaling.

Gene ID: 3636

NCBI Accession: NP_001558

UniProt: O15357

Pathways: Platelet-derived growth Factor Receptor Signaling