PAGR1 antibody (AA 204-254)

Catalog No. ABIN7448711

The Rabbit Polyclonal anti-PAGR1 antibody has been validated for IHC. It is suitable to detect PAGR1 in samples from Human.

Quick Overview for PAGR1 antibody (AA 204-254) (ABIN7448711)

Target: PAGR1 (PAXIP1 Associated Glutamate-Rich Protein 1 (PAGR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAGR1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-PAGR1 Antibody

Binding Specificity: AA 204-254

Purpose: Rabbit anti-PA1 IHC Antibody, Affinity Purified

Predicted Reactivity: Horse,Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,Little brown bat,Small-eared galago,African elephant,Chinese hamster,Thirteen-lined ground squirrel,White-tufted-ear marmoset

Purification: Affinity Purified

Immunogen: Between AA 204 and 254

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PAGR1

Target: PAGR1 (PAXIP1 Associated Glutamate-Rich Protein 1 (PAGR1))

Alternative Name: PA1

Background: Background: PA1 (PTIP-associated protein 1) was isolated as a protein that associates with PTIP (Pax transactivation domain-interacting protein), a nuclear protein involved in the DNA damage response and interacts with the Pax2 transactivation domain. Along with PTIP, PA1 has been found to be present in a MLL3- and MLL4-containing Histone H3 Lysine 4 Methyltransferase complex. PA1 also appears to be important to the DNA damage response and repair. This involvement in DNA damage signaling is reported to be independent of its MLL association. PA1 has also been identified as GAS (glutamate-rich coactivator interacting with SRC1/NCOA1). As an interactor of SRC1 (steroid receptor coactivator 1), PA1 functions as a transcription cofactor.

Gene ID: 79447

NCBI Accession: NP_078792

UniProt: Q9BTK6