This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Expiry Date
12 months
Target
ZAK
(Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
Alternative Name
ZAK
Background
Background: Leucine-zipper and sterile-alpha motif kinase (ZAK) is a mitogen activated protein kinase kinase kinase involved in the S and G2 phase cell cycle checkpoint. ZAK has been shown to activate the stress-activated protein kinase (c-jun N-terminal kinase) pathway and NF-kappaB. It has also been found to be a key mediator of cardiomyocyte hypertrophy and myocardial scars.