Recombinant CD28 antibody (AA 19-140)

Catalog No. ABIN7448899

This Rabbit Monoclonal antibody specifically detects CD28 in IHC and ICC. It exhibits reactivity toward Human.

Quick Overview for Recombinant CD28 antibody (AA 19-140) (ABIN7448899)

Target: CD28

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD28 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: BLR199J

Product Details anti-CD28 Antibody

Binding Specificity: AA 19-140

Purpose: Rabbit anti-CD28 Recombinant Monoclonal Antibody [BLR199J]

Immunogen: residues 19-140 (ECD)

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CD28

Target: CD28

Alternative Name: CD28

Background: Background: CD28 is involved in T-cell activation, the induction of cell proliferation and cytokine production, and promotion of T-cell survival [taken from the Universal Protein Resource (UniProt) P10747].

Gene ID: 940

NCBI Accession: NP_006130

UniProt: P10747

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response