GTF2I antibody (AA 985-998)

Catalog No. ABIN7448971

Product Details anti-GTF2I Antibody

Target: GTF2I (General Transcription Factor III (GTF2I))

Binding Specificity: AA 985-998

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF2I antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Purpose: Rabbit anti-GTF2I/TFII-I IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,Bovine,Dog,Horse,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Chimpanzee,White-tufted-ear marmoset,Tasmanian devil,Small-eared galago,Gray short-tailed opossum,Northern white-cheeked gibbon,Thirteen-lined ground squirrel,Crab-eating macaque,Little brown bat

Purification: Affinity Purified

Immunogen: Between AA 985 and 998

Isotype: IgG

Application Details

Application Notes:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for GTF2I

Target: GTF2I (General Transcription Factor III (GTF2I))

Alternative Name: GTF2I/TFII-I (GTF2I Products)

Background: Background: GTF2I/TFII-I is a multi-functional transcription factor that interacts with the basal transcription machinery and links upstream cellular signals to responsive activator complexes that associate with the C-FOS promoter and other response elements. Haploinsufficiency of GTF2I/TFII-I results in Williams-Beuren syndrome (WBS), a rare developmental disorder characterized by musculo-skeletal and cardiac abnormalities.

Gene ID: 2969

NCBI Accession: NP_127492

UniProt: P78347