PAXIP1 antibody (AA 1-50)

Catalog No. ABIN7449251

The Rabbit Polyclonal anti-PAXIP1 antibody has been validated for WB. It is suitable to detect PAXIP1 in samples from Human.

Quick Overview for PAXIP1 antibody (AA 1-50) (ABIN7449251)

Target: PAXIP1 (PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAXIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PAXIP1 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-PTIP Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PAXIP1

Target: PAXIP1 (PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1))

Alternative Name: PTIP

Background: Background: Pax transactivation domain-interacting protein (PTIP) is implicated in the DNA damage response. PTIP interacts with 53BP1 and PA1 and is part of a Set1-like histone methyltransferase (HMT) complex that also contains ASH2L, RBBP5, WDR5, hDPY-30, NCOA6, a novel protein PA-1 MLL3, MLL4, and UTX. PTIP is therefore suggested to have a role in the regulation of gene expression.

Gene ID: 22976

NCBI Accession: NP_031375

UniProt: Q6ZW49

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response