APOE antibody (HRP)

Catalog No. ABIN7449332

The Goat Polyclonal anti-APOE antibody has been validated for WB and ELISA. It is suitable to detect APOE in samples from Human.

Quick Overview for APOE antibody (HRP) (ABIN7449332)

Target: APOE (Apolipoprotein E (APOE))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This APOE antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA

Clone: H10

Product Details anti-APOE Antibody (HRP)

Purpose: Goat anti-Human Apo E [H10] Antibody HRP Conjugated

Immunogen: Human Apolipoprotein E

Isotype: IgG

Application Details

Application Notes:

WB: 1:1,000 - 1:8,000

ELISA: 1:1,000 - 1:8,000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 50 mM PBS, 0.1 M NaCl, and 0.01 % Thiomersal, pH 7.4

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for APOE

Target: APOE (Apolipoprotein E (APOE))

Alternative Name: ApoE

Background: Background: Apo E contains 299 amino acid residues. It is a 34-37 kDa glycosylated protein (Rall et al., 1983). Apo E is involved with triglyceride, phospholipid, cholesteryl ester, and cholesterol transport in and out of cells and is a ligand for LDL receptors. Apo E has also been implicated in immune and nerve degeneration. It has been found to suppress lymphocyte proliferation. Late-onset familial and sporadic Alzheimer disease patients have been found to have a higher occurrence of one of the three common Apo E isoforms, Apo E4. The Apo E4 isoform has been detected in senile plaques and neurofibrillary tangles of Alzheimer disease patients. Apo E4 is associated with rapid chylomicron-remnant clearance and increased total cholesterol levels.

Gene ID: 348

NCBI Accession: NP_000032

UniProt: P02649

Pathways: Regulation of Cell Size, Lipid Metabolism