ADNP antibody (C-Term)
Quick Overview for ADNP antibody (C-Term) (ABIN7449394)
Target
See all ADNP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Purpose
- Rabbit anti-ADNP Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- between AA 1050 and C-term
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Isotype
- IgG
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Application Notes
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
WB: 1:2,500 - 1:15,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))
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Alternative Name
- ADNP
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Background
- Background: Activity-dependent neuroprotective protein (ADNP) is a factor essential to neurodevelopment. ADNP protein structure consists of nine zinc fingers, a proline-rich region, a nuclear bipartite localization signal, and a homeobox domain profile, suggesting a transcription factor function. ADNP has been shown to differentially associate with chromatin in non-differentiated and neuronal-differentiated cells. ADNP may also mediate the neuroprotective effects of vasoactive intestinal peptide (VIP).
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Gene ID
- 23394
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NCBI Accession
- NP_056154
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UniProt
- Q9H2P0
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Pathways
- Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process
Target
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