STK26/MST4 antibody (AA 300-350)

Catalog No. ABIN7449611

The Rabbit Polyclonal anti-STK26/MST4 antibody has been validated for IP. It is suitable to detect STK26/MST4 in samples from Human.

Quick Overview for STK26/MST4 antibody (AA 300-350) (ABIN7449611)

Target: STK26/MST4 (MST4) (Serine/threonine-Protein Kinase MST4 (MST4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK26/MST4 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Product Details anti-STK26/MST4 Antibody

Binding Specificity: AA 300-350

Purpose: Rabbit anti-MST4/MASK Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: between AA 300 and 350

Isotype: IgG

Application Details

Application Notes:

IP: 1 - 4 μg/mg lysate

WB: Not recommended. Use rabbit anti-MST4/MASK antibody ABIN7452894.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for STK26/MST4

Target: STK26/MST4 (MST4) (Serine/threonine-Protein Kinase MST4 (MST4))

Alternative Name: MST4/MASK

Background: Background: MST4/STK24 is a member of the sterile 20 (Ste20)-like kinase family that acts upstream of mitogen-activated protein kinase (MAPK) pathways and regulates c-Jun N-terminal kinase (JNK), p38 and extracellular signal-regulated kinase (ERK). Ste20-like kinases are involved in a variety of cellular processes which include gene transcription, stress responses, cytoskeletal organization and apoptosis. In response to apoptotic signals, MST4/MASK is cleaved by caspase-3 and mediates apoptosis. MST4/MASK has been shown to influence cell growth and transformation by modulating ERK (extracellular signal-regulated kinase) signaling and may play a role in prostrate cancer. MST4/MASK may also play a role in cell motility.

Gene ID: 51765

NCBI Accession: NP_057626

UniProt: Q9P289