KDM6A antibody (AA 700-750)

Catalog No. ABIN7449926

The Rabbit Polyclonal anti-KDM6A antibody has been validated for WB and IP. It is suitable to detect KDM6A in samples from Human and Mouse.

Quick Overview for KDM6A antibody (AA 700-750) (ABIN7449926)

Target: KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM6A antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-KDM6A Antibody

Binding Specificity: AA 700-750

Purpose: Rabbit anti-UTX Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 700 and 750

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for KDM6A

Target: KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))

Alternative Name: UTX

Background: Background: UTX (ubiquitously transcribed X chromosome tetratricopeptide repeat protein) is a JmjC domain- and tetratricopeptide repeat (TPR) domain- containing protein. UTX functions as a histone demethylase that specifically demethylates 'Lys-27' of histone H3, It demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. UTX plays a central role in regulation of posterior development, by regulating HOX gene expression [taken from the Universal Protein Resource (UniProt) O15550].

Gene ID: 7403

NCBI Accession: NP_066963

UniProt: O15550

Pathways: Tube Formation, Warburg Effect