DBNL antibody (AA 225-275)

Catalog No. ABIN7450326

This anti-DBNL antibody is a Rabbit Polyclonal antibody detecting DBNL in WB and IP. Suitable for Human.

Quick Overview for DBNL antibody (AA 225-275) (ABIN7450326)

Target: DBNL (Drebrin-Like (DBNL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DBNL antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-DBNL Antibody

Binding Specificity: AA 225-275

Purpose: Rabbit anti-HIP55 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 225 and 275

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DBNL

Target: DBNL (Drebrin-Like (DBNL))

Alternative Name: HIP55

Background: Background: HIP55 (HPK1-interacting protein of 55 kDa) is an actin-binding adapter protein that may act as a common effector of antigen receptor-signaling pathways in leukocytes. The association of HIP55 with dynamin suggests that it may also connect the actin cytoskeleton to endocytic function. HIP55 acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes [taken from the Universal Protein Resource (UniProt) Q9UJU6].

Gene ID: 28988

NCBI Accession: NP_001014436

UniProt: Q9UJU6

Pathways: TCR Signaling, Regulation of Actin Filament Polymerization